Open Middle: Horizontal and Vertical Distances (V1)

Creation of this Open Middle exercise was inspired by a problem found in the Grade 6 iReady math curriculum published by Curriculum Associates.
Using digits -9 to 9 no more than one time each, fill in the boxes below to make all statements true. Note: Only positive digits can be placed in the last 3 boxes. Points (soon to appear) are draggable.
Can you create another valid setup that is different from the one above? Try to do so!
What is the greatest possible value you can get for the DIFFERENCE BETWEEN the distances AB and CD (bottom right most box)? Try to make this value as large as you possibly can!
– Tim Brzezinski

Information: Open Middle: Horizontal and Vertical Distances (V1)